Published detection times of drugs used for valid therapeutic purposes in horses.
|
DRUG (BRAND NAME) |
THERAPEUTIC INDICATION |
TYPICAL DOSE and ROUTE* FOR 1000 LB (450 KG) HORSE |
ELIMINATION HALF-LIFE |
DETECTION LIMIT (SOURCE OF INFORMATION) |
|
Tranquilizers/Sedatives |
||||
|
acepromazine (Atravet®, PromAce®) |
Tranquilizer used for calming horses. Has no pain-relieving action. |
25 mg IV, IM 30 mg IM 50 mg Orally |
3 hr (IV) 6 hr (Orally) |
36 hr (Canada) 120 hr (AAEP) 72 hr (Australia) |
|
butorphanol (Torbugesic®) |
Sedative with pain-relieving action, used frequently to treat colic in horses. |
5 mg IV |
4 hr |
72 hr (Canada) |
|
dantrolene (Dantrium®) |
Muscle relaxant used in horses with myopathies ("tying-up"). |
1 gram Orally |
2 hr |
36 hr (Canada) |
|
detomidine (Dormosedan®) |
Sedative with pain-relieving action, used frequently to treat colic in horses. |
5 mg IV |
1 hr |
48 hr (Australia) 72 hr (Canada) |
|
guaifenesin (Guailaxin®, Gecolate®) |
Muscle relaxant used in horses with myopathies ("tying-up"). |
2 gram IV, Orally |
1.5 hr |
24 hr (Canada) 48 hr (Australia) |
|
methocarbamol (Robaxin®) |
Muscle relaxant used in horses with myopathies ("tying-up"). |
5 grams IV, Orally |
1 hr |
24 hr (Canada) |
|
romifidine (Sedivet®) |
Sedative with pain-relieving action, used frequently to treat colic in horses. |
30 mg IV |
NA** |
48 hr (Australia) |
|
Anti-inflammatories/Pain Relievers |
||||
|
aspirin |
Orallyor pain-reliever in the horse. Sometimes used to treat periodic ophthalmia ("moon blindness"), laminitis, and colic due to parasite damage. |
11.7 grams Orally |
1 hr |
24 hr (Canada) |
|
dimethylsulfoxide (DMSO) |
Applied topically as an anti-inflammatory agent, given IV to treat myopathies and increase urination. |
19.8 grams topically |
9 hr |
36 hr (Canada) 72 hr (AAEP) |
|
450 mg IV |
|
96 hr (AAEP) |
||
|
dipyrone (Novin®) |
Nonsteroidal anti-inflammatory drug used to treat colic and musculoskeletal pain and inflammation. |
10 grams IV, IM |
NA |
120 hr (Canada) 15 days (ELISA test - AAEP) |
|
flunixin meglumine (Banamine®) |
Nonsteroidal anti-inflammatory drug used to treat colic and musculoskeletal pain and inflammation. |
450 mg IV, Orally |
1.6 hr |
72 hr (Canada) 72 hr (Australia) 15 days (ELISA - AAEP) |
|
ketoprofen (Ketofen®, Anafen®) |
Nonsteroidal anti-inflammatory drug used to treat colic and musculoskeletal pain and inflammation. |
1 gram IV |
1.5 hr |
48 hr (Canada) 72 hr (Australia, AAEP) |
|
lidocaine (Xylocaine®) |
Local anesthetic used to block nerves. |
150 mg SC |
1 hr |
24 hr (Canada) |
|
meclofenamic acid (Arquel®) |
Nonsteroidal anti-inflammatory drug used to treat colic and musculoskeletal pain and inflammation. |
1 gram Orally |
8 hr |
48 hr (Canada) 72 hr (Australia) |
|
mepivicaine (Carbocaine®) |
Local anesthetic used to block nerves. |
300 mg SC, IA |
3 hr |
48 hr (Canada, Australia) |
|
naproxen (Equiproxen, Aleeve®) |
Nonsteroidal anti-inflammatory drug used to treat colic and musculoskeletal pain and inflammation. |
2 grams Orally |
4 hr |
120 hr (Canada) |
|
phenylbutazone ("Bute") |
Nonsteroidal anti-inflammatory drug used to treat colic and musculoskeletal pain and inflammation. |
3 grams, IV, Orally |
11 hr |
96 hr (Canada) 120 hr (Australia) |
|
procaine (Novocaine®) |
Local anesthetic used to block nerves. |
200 mg SC |
2 hr IM 1 hr SC |
48 hr (Canada) |
|
procaine penicillin G |
Combined with penicillin to make the antibiotic slowly absorbed from the injection site, to give it a long duration of antibacterial action. |
4 million International Units IM |
10 hr |
425 hr (Canada) |
|
Corticosteroids |
||||
|
betamethasone (Betasone®, Celestone®) |
Anti-inflammatory; allergic reactions. |
35 mg IM |
NA |
24 hr (Canada) > 7 days (Australia) |
|
dexamethasone (Azium®) |
Anti-inflammatory; allergic reactions. |
25 mg IV, IM 10 mg Orally |
4 hr |
24 hr (Canada) 48 hr (Australia) 144 hr (ELISA - AAEP) |
|
flumethasone (Flucort®) |
Anti-inflammatory; allergic reactions. |
5 mg IV, IM |
NA |
24 hr (Canada) |
|
isoflupredone (Predef 2X®) |
Anti-inflammatory; allergic reactions. |
24 mg IM |
NA |
48 hr (Canada) |
|
methylprednisolone acetate (Depo-Medrol®) |
Anti-inflammatory; allergic reactions. |
200 mg IA, IM |
9 days |
96 hr (Canada) 222 hr (ELISA - AAEP) > 45 days (Australia) |
|
prednisolone |
Anti-inflammatory; allergic reactions. |
150 mg IV |
1.65 hr |
24 hr (Canada) |
|
prednisone |
Anti-inflammatory; allergic reactions. |
1 gram Orally |
2 hr |
24 hr (Canada) |
|
triamcinolone (Vetalog®) |
Anti-inflammatory; allergic reactions. |
24 mg IM |
2 hr |
24 hr (Canada) 15 days (Australia) |
|
|
|
30 mg IA |
|
72 hr (Australia) 96 hr (Canada) |
|
Miscellaneous Drugs |
||||
|
aminophylline |
Opens airways in horses with "heaves". |
1.5 grams IV |
NA |
96 hr (Canada) |
|
theophylline |
Opens airways in horses with "heaves". |
6 grams Orally |
NA |
>7 days (Australia) |
|
clenbuterol (Ventipulmin®) |
Opens airways in horses with "heaves". |
0.4 mg Orally |
NA |
72 hr (Canada) |
|
dembrexine (Sputolysin®) |
Expectorant for horses with "heaves". |
150 mg Orally |
NA |
72 hr (Canada) |
|
diphenhydramine (Benadryl®) |
Antihistamine. |
500 mg Orally |
NA |
48 hr (Canada, Australia) |
|
isoxuprine (Vasodilan®) |
Dilates blood vessels, used for treatment of navicular disease. |
300 mg Orally |
3 hr |
36 hr (Canada) weeks-months (ELISA - AAEP) |
* IV - intravenous, IM - Intramuscular, SC - Subcutaneous, IA - Intra-articular (into the joint)
** No information available.